High-level mupirocin resistance within methicillin-resistant Staphylococcus aureus pandemic lineages.

نویسندگان

  • Eduardo Pérez-Roth
  • Celeste López-Aguilar
  • Julia Alcoba-Florez
  • Sebastián Méndez-Alvarez
چکیده

The methicillin-resistant Staphylococcus aureus (MRSA) population in the Hospital Universitario Nuestra Señora de Candelaria over a 5-year period (1998 to 2002) was marked by shifts in the circulation of pandemic clones. Here, we investigated the emergence of high-level mupirocin resistance (Hi-Mup(r)). In addition to clonal spread, transfer of ileS2-carrying plasmids played a significant role in the dissemination of Hi-Mup(r) among pandemic MRSA lineages.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 50 9  شماره 

صفحات  -

تاریخ انتشار 2006